The goal of the Krause Laboratory is to define how stem and progenitor cells balance and regulate fate decisions in health and disease. We study stem cells to improve strategies for repair and regeneration of the hematopoietic system as well as solid organs including the lung and parathyroids. Situated in the Yale Stem Cell Center at the Yale School of Medicine, we develop cellular models of hematopoiesis using bone marrow derived stem and progenitor cells. With Diane serving as Medical Director of the Advanced Cell Therapy Laboratory, the lab is uniquely situated to translate insights from basic research into improved strategies for bone marrow and stem cell transplantation and novel treatments for leukemia and lymphoma.
The Krause Laboratory is a diverse group of driven individuals united by a common drive to better understand the world of biology. Visit our lab members page to meet the team.
A selection of our ongoing research.
Using bone marrow derived stem and progenitor cells to understand blood development and cancer
Studying the genetic dysregulation that causes Acute Megakaryoblastic Leukemia
Transcriptional and epigenetic control of megakaryocyte maturation
Using stem cells to restore parathyroid function
Producing cell therapy products for bone marrow transplantation and clinical trials
Posts from Diane about science, medicine, and the lab.
If you have any question about the lab, please fill out the form to the right to send an email to Diane.